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EG-15 THE METHYLATION STATUS OF MGMT IN MEDULLOBLASTOMA

BACKGROUND: Medulloblastoma is a highly malignant brain tumor in childhood. Some studies reported that alkylating chemotherapeutic drugs are effective agents in the treatment of patients with medulloblastoma. O(6)-methylguanine-DNA methyltransferase (MGMT) is one of the DNA repair enzymes and plays...

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Autors principals: Shimizu, Yuzaburo, Kurimoto, Tomoko, Kondo, Akihide, Arai, Hajime
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218093/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou254.15
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