Cerebrospinal Fluid α-Synuclein Predicts Cognitive Decline in Parkinson Disease Progression in the DATATOP Cohort

Most patients with Parkinson disease (PD) develop both cognitive and motor impairment, and biomarkers for progression are urgently needed. Although α-synuclein is altered in cerebrospinal fluid of patients with PD, it is not known whether it predicts motor or cognitive deterioration. We examined cli...

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Bibliografiske detaljer
Main Authors: Stewart, Tessandra, Liu, Changqin, Ginghina, Carmen, Cain, Kevin C., Auinger, Peggy, Cholerton, Brenna, Shi, Min, Zhang, Jing
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2014
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969999/
https://ncbi.nlm.nih.gov/pubmed/24625392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.12.007
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