Longitudinal Analyses of Cerebrospinal Fluid α-Synuclein in Prodromal and Early Parkinson’s Disease

BACKGROUND: Aggregation of α-synuclein is central to the pathophysiology of PD. Biomarkers related to α-synuclein may be informative for PD diagnosis/progression. OBJECTIVES: To analyze α-synuclein in CSF in drug-naïve PD, healthy controls, and prodromal PD in the Parkinson’s Progression Markers Ini...

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Détails bibliographiques
Publié dans:Mov Disord
Auteurs principaux: Mollenhauer, Brit, Caspell-Garcia, Chelsea J., Coffey, Christopher S., Taylor, Peggy, Singleton, Andy, Shaw, Leslie M., Trojanowski, John Q., Frasier, Mark, Simuni, Tanya, Iranzo, Alex, Oertel, Wolfgang, Siderowf, Andrew, Weintraub, Daniel, Seibyl, John, Toga, Arthur W., Tanner, Caroline M., Kieburtz, Karl, Chahine, Lana M., Marek, Kenneth, Galasko, Douglas
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098385/
https://ncbi.nlm.nih.gov/pubmed/31361367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.27806
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