Cerebrospinal Fluid α-Synuclein Predicts Cognitive Decline in Parkinson Disease Progression in the DATATOP Cohort

Most patients with Parkinson disease (PD) develop both cognitive and motor impairment, and biomarkers for progression are urgently needed. Although α-synuclein is altered in cerebrospinal fluid of patients with PD, it is not known whether it predicts motor or cognitive deterioration. We examined cli...

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Main Authors: Stewart, Tessandra, Liu, Changqin, Ginghina, Carmen, Cain, Kevin C., Auinger, Peggy, Cholerton, Brenna, Shi, Min, Zhang, Jing
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Investigative Pathology 2014
Ábhair:
Regular Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969999/
https://ncbi.nlm.nih.gov/pubmed/24625392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.12.007
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