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Cerebrospinal Fluid α-Synuclein Predicts Cognitive Decline in Parkinson Disease Progression in the DATATOP Cohort

Most patients with Parkinson disease (PD) develop both cognitive and motor impairment, and biomarkers for progression are urgently needed. Although α-synuclein is altered in cerebrospinal fluid of patients with PD, it is not known whether it predicts motor or cognitive deterioration. We examined cli...

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Detalhes bibliográficos
Main Authors: Stewart, Tessandra, Liu, Changqin, Ginghina, Carmen, Cain, Kevin C., Auinger, Peggy, Cholerton, Brenna, Shi, Min, Zhang, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969999/
https://ncbi.nlm.nih.gov/pubmed/24625392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.12.007
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