Phosphorylated α-synuclein in Parkinson’s disease: correlation depends on disease severity

INTRODUCTION: α-Synuclein (α-syn) is a key protein in Parkinson’s disease (PD), and one of its phosphorylated forms, pS129, is higher in PD patients than healthy controls. However, few studies have examined its levels in longitudinally collected cerebrospinal fluid (CSF) or in preclinical cases. In...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Stewart, Tessandra, Sossi, Vesna, Aasly, Jan O, Wszolek, Zbigniew K, Uitti, Ryan J, Hasegawa, Kazuko, Yokoyama, Teruo, Zabetian, Cyrus P, Leverenz, James B, Stoessl, Alexander Jon, Wang, Yu, Ginghina, Carmen, Liu, Changqin, Cain, Kevin C, Auinger, Peggy, Kang, Un Jung, Jensen, Poul Henning, Shi, Min, Zhang, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362824/
https://ncbi.nlm.nih.gov/pubmed/25637461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0185-3
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