Phosphorylated α-synuclein in Parkinson’s disease: correlation depends on disease severity

INTRODUCTION: α-Synuclein (α-syn) is a key protein in Parkinson’s disease (PD), and one of its phosphorylated forms, pS129, is higher in PD patients than healthy controls. However, few studies have examined its levels in longitudinally collected cerebrospinal fluid (CSF) or in preclinical cases. In...

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Vydáno v:Acta Neuropathol Commun
Hlavní autoři: Stewart, Tessandra, Sossi, Vesna, Aasly, Jan O, Wszolek, Zbigniew K, Uitti, Ryan J, Hasegawa, Kazuko, Yokoyama, Teruo, Zabetian, Cyrus P, Leverenz, James B, Stoessl, Alexander Jon, Wang, Yu, Ginghina, Carmen, Liu, Changqin, Cain, Kevin C, Auinger, Peggy, Kang, Un Jung, Jensen, Poul Henning, Shi, Min, Zhang, Jing
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362824/
https://ncbi.nlm.nih.gov/pubmed/25637461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0185-3
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