TORC1 and class I HDAC inhibitors synergize to suppress mature B cell neoplasms

Enhanced proliferative signaling and loss of cell cycle regulation are essential for cancer progression. Increased mitogenic signaling through activation of the mTOR pathway, coupled with deregulation of the Cyclin D/retinoblastoma (Rb) pathway is a common feature of lymphoid malignancies, including...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Simmons, John K., Patel, Jyoti, Michalowski, Aleksandra, Zhang, Shuling, Wei, Bih-Rong, Sullivan, Patrick, Gamache, Ben, Felsenstein, Kenneth, Kuehl, W. Michael, Simpson, R. Mark, Zingone, Adriana, Landgren, Ola, Mock, Beverly A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2013
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969848/
https://ncbi.nlm.nih.gov/pubmed/24429254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.11.007
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