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Human Endoplasmic Reticulum Mannosidase I Is Subject to Regulated Proteolysis
In the early secretory pathway, opportunistic cleavage of asparagine-linked oligosaccharides by endoplasmic reticulum (ER) mannosidase I targets misfolded glycoproteins for dislocation into the cytosol and destruction by 26 S proteasomes. The low basal concentration of the glycosidase is believed to...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2006
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3969733/ https://ncbi.nlm.nih.gov/pubmed/17166854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M607156200 |
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