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Requirement of NK cells for selective A(2A r)eceptor blockade to suppress CD73(+) tumor metastasis

CD73 is becoming an emerging therapeutic target for the prevention of tumor growth and metastasis. However, the mechanism by which CD73 promotes tumor metastasis is unclear. Beavis et al. evaluated the efficacy of A(2A) and A(2B) adenosine receptor antagonists in inhibiting the metastasis of tumors...

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Bibliographic Details
Main Authors: Qin, Lei, Thompson, Linda F, Kuzel, Timothy M, Zhang, Bin
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968679/
https://ncbi.nlm.nih.gov/pubmed/24341879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.13.154
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