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Requirement of NK cells for selective A(2A r)eceptor blockade to suppress CD73(+) tumor metastasis

CD73 is becoming an emerging therapeutic target for the prevention of tumor growth and metastasis. However, the mechanism by which CD73 promotes tumor metastasis is unclear. Beavis et al. evaluated the efficacy of A(2A) and A(2B) adenosine receptor antagonists in inhibiting the metastasis of tumors...

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Autori principali: Qin, Lei, Thompson, Linda F, Kuzel, Timothy M, Zhang, Bin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968679/
https://ncbi.nlm.nih.gov/pubmed/24341879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.13.154
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