Combination antiretroviral therapy (cART) component ritonavir significantly alters docetaxel exposure

PURPOSE: Non-AIDS defining cancers (NADCs) now exceed rates of AIDS-defining cancers in HIV-positive patients. Treatment of NADCs may be complicated by drug-drug interactions between antiretrovirals and chemotherapy. Docetaxel is a widely used anticancer agent that is primarily metabolized by CYP3A4...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rudek, Michelle A, Chang, Cathy Y., Steadman, Kenneth, Johnson, Michael D., Desai, Naveen, Deeken, John F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968228/
https://ncbi.nlm.nih.gov/pubmed/24488374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-014-2399-7
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