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Preclinical assessment of the interactions between the antiretroviral drugs, ritonavir and efavirenz, and the tyrosine kinase inhibitor erlotinib

PURPOSE: Prevalence of non-AIDS-defining cancers (NADCs) has increased in the era of potent antiretroviral treatments. Incidence rates of NADCs now exceed AIDS-defining cancers in HIV-positive patients. Treatment of NADCs may be complicated by interactions between antiretrovirals and chemotherapy mo...

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Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: Deeken, John F., Beumer, Jan H., Anders, Nicole M., Wanjiku, Teresia, Rusnak, Milan, Rudek, Michelle A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577782/
https://ncbi.nlm.nih.gov/pubmed/26330331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-015-2856-y
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