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Combination antiretroviral therapy (cART) component ritonavir significantly alters docetaxel exposure
PURPOSE: Non-AIDS defining cancers (NADCs) now exceed rates of AIDS-defining cancers in HIV-positive patients. Treatment of NADCs may be complicated by drug-drug interactions between antiretrovirals and chemotherapy. Docetaxel is a widely used anticancer agent that is primarily metabolized by CYP3A4...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3968228/ https://ncbi.nlm.nih.gov/pubmed/24488374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-014-2399-7 |
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