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Exposure to previous cART is associated with significant liver fibrosis and cirrhosis in human immunodeficiency virus-infected patients

INTRODUCTION: Combined antiretroviral therapy (cART) has improved survival in HIV-patients. While the first antiretrovirals, which became available in particular D-drugs (especially didanosine and stavudine) and unboosted protease inhibitors, may impair liver function, the modern cART seems to decre...

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Veröffentlicht in:PLoS One
Hauptverfasser: Anadol, Evrim, Lust, Kristina, Boesecke, Christoph, Schwarze-Zander, Carolynne, Mohr, Raphael, Wasmuth, Jan-Christian, Rockstroh, Jürgen Kurt, Trebicka, Jonel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773180/
https://ncbi.nlm.nih.gov/pubmed/29346443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191118
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