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A robust and rapid liquid chromatography tandem mass spectrometric method for the quantitative analysis of 5-azacytidine
The DNA methyltransferase inhibitor 5-azacytidine is being evaluated clinically as an oral formulation to treat various solid tumors. A sensitive, reliable method was developed to quantitate 5-azacytidine using LC-MS/MS to perform detailed pharmacokinetic studies. The drug of interest was extracted...
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| Publicado no: | Biomed Chromatogr |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4713385/ https://ncbi.nlm.nih.gov/pubmed/26174363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bmc.3562 |
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