Validation of a Liquid Chromatography-Tandem Mass Spectrometric Assay for Quantitative Analysis of Lenvatinib in Human Plasma

Toward conducting clinical pharmacokinetic studies of an antineoplastic agent, lenvatinib, we developed a liquid chromatography-tandem mass spectrometric assay for its quantitative analysis in human plasma. Analyte (lenvatinib) and internal standard (IS, propranolol) in the plasma were extracted by...

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Detalhes bibliográficos
Publicado no:Int J Anal Chem
Main Authors: Ogawa-Morita, Tomoko, Sano, Yoshiyuki, Okano, Tomoka, Fujii, Hirofumi, Tahara, Makoto, Yamaguchi, Masakazu, Minami, Hironobu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478828/
https://ncbi.nlm.nih.gov/pubmed/28680445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/2341876
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