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A liquid chromatography/tandem mass spectrometry assay to quantitate MS-275 in human plasma

A rapid, sensitive and selective method was developed and validated using LC/MS/MS for determination of MS-275 in human plasma. Sample preparation involved a single step liquid-liquid extraction by the addition of 0.2 ml of plasma with 5 ml acetonitrile/n-butyl-chloride. Separation of the compounds...

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Detalhes bibliográficos
Main Authors: Zhao, Ming, Rudek, Michelle A., Mnasakanyan, Aleksandr, Hartke, Carol, Pili, Roberto, Baker, Sharyn D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797151/
https://ncbi.nlm.nih.gov/pubmed/16971082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2006.08.006
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