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Development and evaluation of a novel microemulsion formulation of elacridar to improve its bioavailability
The study objective was to develop a formulation of elacridar to overcome its dissolution-rate limited bioavailability. Elacridar is a P-gp and BCRP inhibitor that has been used to improve the brain distribution of drugs that are substrates of P-gp and BCRP. The chronic use of elacridar is restricte...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3967790/ https://ncbi.nlm.nih.gov/pubmed/23334925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23450 |
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