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Effects of mutations and deletions in the human optineurin gene

Optineurin is a gene associated with normal tension glaucoma (NTG) and amyotrophic lateral sclerosis (ALS). Foci formation and functional consequences including Golgi fragmentation, impairment of vesicle trafficking and apoptosis were observed previously upon overexpression and/or mutation of optine...

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Hlavní autoři: Turturro, Sanja, Shen, Xiang, Shyam, Rajalekshmy, Yue, Beatrice YJT, Ying, Hongyu
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967732/
https://ncbi.nlm.nih.gov/pubmed/24683533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-3-99
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