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Induction of autophagy in rats upon overexpression of wild-type and mutant optineurin gene
BACKGROUND: Optineurin is a gene associated with normal tension glaucoma and amyotrophic lateral sclerosis. It has been reported previously that in cultured RGC5 cells, the turnover of endogenous optineurin involves mainly the ubiquitin-proteasome pathway (UPP). When optineurin is upregulated or mut...
Shranjeno v:
| izdano v: | BMC Cell Biol |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4429416/ https://ncbi.nlm.nih.gov/pubmed/25943884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-015-0060-x |
| Oznake: |
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