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Effects of mutations and deletions in the human optineurin gene

Optineurin is a gene associated with normal tension glaucoma (NTG) and amyotrophic lateral sclerosis (ALS). Foci formation and functional consequences including Golgi fragmentation, impairment of vesicle trafficking and apoptosis were observed previously upon overexpression and/or mutation of optine...

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Detalhes bibliográficos
Main Authors: Turturro, Sanja, Shen, Xiang, Shyam, Rajalekshmy, Yue, Beatrice YJT, Ying, Hongyu
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967732/
https://ncbi.nlm.nih.gov/pubmed/24683533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-3-99
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