Differential Effects of Myocilin and Optineurin, Two Glaucoma Genes, on Neurite Outgrowth

Myocilin and optineurin are two genes linked to glaucoma, a major blinding disease characterized by progressive loss of retinal ganglion cells (RGCs) and their axons. To investigate the effects of force-expressed wild-type and mutant myocilin and optineurin on neurite outgrowth in neuronal cells, we...

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Main Authors: Koga, Takahisa, Shen, Xiang, Park, Jeong-Seok, Qiu, Ye, Park, Bum-Chan, Shyam, Rajalekshmy, Yue, Beatrice Y.J.T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797895/
https://ncbi.nlm.nih.gov/pubmed/19959812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090194
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