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Rational design of substituted diarylureas: a scaffold for binding to G-quadruplex motifs
The design and synthesis of a series of urea-based non-polycyclic aromatic ligands with alkylaminoanilino side chains as telomeric and genomic G-quadruplex DNA interacting agents is described. Their interactions with quadruplexes have been examined by means of Fluorescent Resonance Energy Transfer m...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3967098/ https://ncbi.nlm.nih.gov/pubmed/19053833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm801245v |
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