Polycystin-1 Binds Par3/aPKC and Controls Convergent Extension During Renal Tubular Morphogenesis

Several organs, including lungs and kidneys, are formed by epithelial tubes whose proper morphogenesis ensures correct function. This is best exemplified by the kidney, where defective establishment or maintanance of tubular diameter results in polycystic kidney disease, a common genetic disorder. M...

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Autors principals: Castelli, Maddalena, Boca, Manila, Chiaravalli, Marco, Ramalingam, Harini, Rowe, Isaline, Distefano, Gianfranco, Carroll, Thomas, Boletta, Alessandra
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967097/
https://ncbi.nlm.nih.gov/pubmed/24153433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3658
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