Pan-cancer patterns of somatic copy-number alteration

Determining how somatic copy-number alterations (SCNAs) promote cancer is an important goal. We characterized SCNA patterns among 4934 cancers from The Cancer Genome Atlas Pan-Cancer dataset. Whole-genome doubling, observed in 37% of cancers, was associated with higher rates of every other type of S...

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Detalhes bibliográficos
Main Authors: Zack, Travis I., Schumacher, Steven E., Carter, Scott L., Cherniack, Andrew D., Saksena, Gordon, Tabak, Barbara, Lawrence, Michael S., Zhang, Cheng-Zhong, Wala, Jeremiah, Mermel, Craig H., Sougnez, Carrie, Gabriel, Stacey B., Hernandez, Bryan, Shen, Hui, Laird, Peter W., Getz, Gad, Meyerson, Matthew, Beroukhim, Rameen
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966983/
https://ncbi.nlm.nih.gov/pubmed/24071852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2760
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