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Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo

RNA plays a dual role as an informational molecule and a direct effector of biological tasks. The latter function is enabled by RNA’s ability to adopt complex secondary and tertiary folds and thus has motivated extensive computational(1–2) and experimental(3–8) efforts for determining RNA structures...

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Detalhes bibliográficos
Main Authors: Rouskin, Silvi, Zubradt, Meghan, Washietl, Stefan, Kellis, Manolis, Weissman, Jonathan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966492/
https://ncbi.nlm.nih.gov/pubmed/24336214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12894
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