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DMS-MaPseq for genome-wide or targeted RNA structure probing in vivo
Coupling structure-specific in vivo chemical modification to next-generation sequencing is transforming RNA secondary structural studies in living cells. The dominant strategy for detecting in vivo chemical modifications uses reverse transcriptase truncation products, which introduces biases and nec...
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| Publicado no: | Nat Methods |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5508988/ https://ncbi.nlm.nih.gov/pubmed/27819661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4057 |
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