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miCLIP-MaPseq, a Substrate Identification Approach for Radical SAM RNA Methylating Enzymes
Although present across bacteria, the large family of radical SAM RNA methylating enzymes is largely uncharacterized. Escherichia coli RlmN, the founding member of the family, methylates an adenosine in 23S rRNA and several tRNAs to yield 2-methyladenosine (m(2)A). However, varied RNA substrate spec...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7207077/ https://ncbi.nlm.nih.gov/pubmed/29782154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b02618 |
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