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The CARD plays a critical role in ASC foci formation and inflammasome signaling
The apoptosis-associated speck-like protein (ASC) is a key component of multimeric protein complexes that mediate inflammation and host defense. Composed of a Pyrin (PYD) domain and a caspase activation and recruitment domain (CARD), ASC functions downstream of nucleotide-binding domain, leucine-ric...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3966062/ https://ncbi.nlm.nih.gov/pubmed/23110696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20121198 |
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