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Structural Mechanisms in NLR inflammasome signaling

Members of the NOD-like receptor (NLR) family mediate the innate immune response to a wide range of pathogens, tissue damage and other cellular stresses. They achieve modulation of these signals by forming oligomeric signaling platforms, which in analogy to the apoptosome are predicted to adopt a de...

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Detalhes bibliográficos
Publicado no:Curr Opin Struct Biol
Main Authors: Lechtenberg, Bernhard C, Mace, Peter D, Riedl, Stefan J
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268015/
https://ncbi.nlm.nih.gov/pubmed/25201319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2014.08.011
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