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Rosetta stone of NLR innate immunity

The formation of NLR inflammasomes is a central step in the initiation of the innate immune response. Two recent publications describe the structure of the NAIP2-NLRC4 inflammasome and derive an elegant model of NLR inflammasome formation, whereby binding of the pathogen-molecule-bound NLR NAIP2 to...

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Detalles Bibliográficos
Publicado en:Trends Biochem Sci
Main Authors: Lechtenberg, Bernhard C., Riedl, Stefan J.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706488/
https://ncbi.nlm.nih.gov/pubmed/26631419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2015.11.008
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