Homotypic CARD-CARD interaction is critical for the activation of NLRP1 inflammasome

Cytosolic inflammasomes are supramolecular complexes that are formed in response to intracellular pathogens and danger signals. However, as to date, the detailed description of a homotypic caspase recruitment domain (CARD) interaction between NLRP1 and ASC has not been presented. We found the CARD–C...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Xu, Zhihao, Zhou, Ying, Liu, Muziying, Ma, Huan, Sun, Liangqi, Zahid, Ayesha, Chen, Yulei, Zhou, Rongbin, Cao, Minjie, Wu, Dabao, Zhao, Weidong, Li, Bofeng, Jin, Tengchuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7801473/
https://ncbi.nlm.nih.gov/pubmed/33431827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03342-8
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