Homotypic CARD-CARD interaction is critical for the activation of NLRP1 inflammasome

Cytosolic inflammasomes are supramolecular complexes that are formed in response to intracellular pathogens and danger signals. However, as to date, the detailed description of a homotypic caspase recruitment domain (CARD) interaction between NLRP1 and ASC has not been presented. We found the CARD–C...

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Vydáno v:Cell Death Dis
Hlavní autoři: Xu, Zhihao, Zhou, Ying, Liu, Muziying, Ma, Huan, Sun, Liangqi, Zahid, Ayesha, Chen, Yulei, Zhou, Rongbin, Cao, Minjie, Wu, Dabao, Zhao, Weidong, Li, Bofeng, Jin, Tengchuan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7801473/
https://ncbi.nlm.nih.gov/pubmed/33431827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03342-8
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