The transcription factors T-bet and Runx are required for the ontogeny of pathogenic interferon-γ-producing T helper 17 cells

T helper 17 (Th17) cells can give rise to interleukin-17A (IL-17A) and interferon (IFN)-γ-double producing cells that are implicated in development of autoimmune diseases. However, the molecular mechanisms that govern generation of IFN-γ-producing Th17 cells are unclear. We found that co-expression...

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Detalhes bibliográficos
Main Authors: Wang, Yan, Godec, Jernej, Ben-Aissa, Khadija, Cui, Kairong, Zhao, Keji, Pucsek, Alexandra B., Lee, Yun Kyung, Weaver, Casey T., Yagi, Ryoji, Lazarevic, Vanja
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965587/
https://ncbi.nlm.nih.gov/pubmed/24530058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.01.002
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