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Ikaros Silences T-bet Expression and Interferon-γ Production during T Helper 2 Differentiation

CD4+ T cells can be instructed by nonantigen-specific signals to differentiate into functionally distinct lineages with mutually exclusive patterns of cytokine production. The molecular events that drive interferon-γ (IFNγ) production during Th1 development are well understood, but mechanisms that s...

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Detalhes bibliográficos
Main Authors: Thomas, Rajan M., Chen, Chunxia, Chunder, Neelanjana, Ma, Lingzhi, Taylor, Justin, Pearce, Edward J., Wells, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807311/
https://ncbi.nlm.nih.gov/pubmed/19923223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.038794
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