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Ikaros and GATA-1 Combinatorial Effect Is Required for Silencing of Human γ-Globin Genes

During development and erythropoiesis, globin gene expression is finely modulated through an important network of transcription factors and chromatin modifying activities. In this report we provide in vivo evidence that endogenous Ikaros is recruited to the human β-globin locus and targets the histo...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Bottardi, Stefania, Ross, Julie, Bourgoin, Vincent, Fotouhi-Ardakani, Nasser, Affar, El Bachir, Trudel, Marie, Milot, Eric
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology (ASM) 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648246/
https://ncbi.nlm.nih.gov/pubmed/19114560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01523-08
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