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Ikaros and GATA-1 Combinatorial Effect Is Required for Silencing of Human γ-Globin Genes

During development and erythropoiesis, globin gene expression is finely modulated through an important network of transcription factors and chromatin modifying activities. In this report we provide in vivo evidence that endogenous Ikaros is recruited to the human β-globin locus and targets the histo...

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Detalhes bibliográficos
Main Authors: Bottardi, Stefania, Ross, Julie, Bourgoin, Vincent, Fotouhi-Ardakani, Nasser, Affar, El Bachir, Trudel, Marie, Milot, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648246/
https://ncbi.nlm.nih.gov/pubmed/19114560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01523-08
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