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Ikaros and GATA-1 Combinatorial Effect Is Required for Silencing of Human γ-Globin Genes

During development and erythropoiesis, globin gene expression is finely modulated through an important network of transcription factors and chromatin modifying activities. In this report we provide in vivo evidence that endogenous Ikaros is recruited to the human β-globin locus and targets the histo...

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Hlavní autoři: Bottardi, Stefania, Ross, Julie, Bourgoin, Vincent, Fotouhi-Ardakani, Nasser, Affar, El Bachir, Trudel, Marie, Milot, Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648246/
https://ncbi.nlm.nih.gov/pubmed/19114560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01523-08
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