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Ikaros and GATA-1 Combinatorial Effect Is Required for Silencing of Human γ-Globin Genes
During development and erythropoiesis, globin gene expression is finely modulated through an important network of transcription factors and chromatin modifying activities. In this report we provide in vivo evidence that endogenous Ikaros is recruited to the human β-globin locus and targets the histo...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2648246/ https://ncbi.nlm.nih.gov/pubmed/19114560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01523-08 |
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