The IKAROS Interaction with a Complex Including Chromatin Remodeling and Transcription Elongation Activities Is Required for Hematopoiesis

IKAROS is a critical regulator of hematopoietic cell fate and its dynamic expression pattern is required for proper hematopoiesis. In collaboration with the Nucleosome Remodeling and Deacetylase (NuRD) complex, it promotes gene repression and activation. It remains to be clarified how IKAROS can sup...

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Détails bibliographiques
Publié dans:PLoS Genet
Auteurs principaux: Bottardi, Stefania, Mavoungou, Lionel, Pak, Helen, Daou, Salima, Bourgoin, Vincent, Lakehal, Yahia A., Affar, El Bachir, Milot, Eric
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256266/
https://ncbi.nlm.nih.gov/pubmed/25474253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004827
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