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NPM and NPM-MLF1 interact with chromatin remodeling complexes and influence their recruitment to specific genes

Nucleophosmin (NPM1) is frequently mutated or subjected to chromosomal translocation in acute myeloid leukemia (AML). NPM protein is primarily located in the nucleus, but the recurrent NPMc+ mutation, which creates a nuclear export signal, is characterized by cytoplasmic localization and leukemogeni...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:PLoS Genet
Main Authors: Darracq, Anaïs, Pak, Helen, Bourgoin, Vincent, Zmiri, Farah, Dellaire, Graham, Affar, El Bachir, Milot, Eric
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6853375/
https://ncbi.nlm.nih.gov/pubmed/31675375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008463
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