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Ikaros and GATA-1 Combinatorial Effect Is Required for Silencing of Human γ-Globin Genes
During development and erythropoiesis, globin gene expression is finely modulated through an important network of transcription factors and chromatin modifying activities. In this report we provide in vivo evidence that endogenous Ikaros is recruited to the human β-globin locus and targets the histo...
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| Huvudupphovsmän: | , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Microbiology (ASM)
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2648246/ https://ncbi.nlm.nih.gov/pubmed/19114560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01523-08 |
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