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The transcription factors T-bet and Runx are required for the ontogeny of pathogenic interferon-γ-producing T helper 17 cells
T helper 17 (Th17) cells can give rise to interleukin-17A (IL-17A) and interferon (IFN)-γ-double producing cells that are implicated in development of autoimmune diseases. However, the molecular mechanisms that govern generation of IFN-γ-producing Th17 cells are unclear. We found that co-expression...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3965587/ https://ncbi.nlm.nih.gov/pubmed/24530058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.01.002 |
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