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Selective Inhibition of Late Sodium Current Suppresses Ventricular Tachycardia and Fibrillation in Intact Rat Hearts
BACKGROUND: Enhanced late inward Na current (I(Na-L)) modulates action potential duration (APD) and plays a key role in the genesis of early and delayed afterdepolarizations (EADs & DADs) and triggered activity. OBJECTIVES: To define the influence of selective block of the I(Na-L) on EAD- &...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3963462/ https://ncbi.nlm.nih.gov/pubmed/24291413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2013.11.026 |
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