Enhanced Late Na and Ca Currents as Effective Antiarrhythmic Drug Targets

While recent advances clarified the molecular and cellular modes of action of antiarrhythmic drugs (AADs), their link to suppression of dynamical arrhythmia mechanisms remains only partially understood. The current classifications of AADs (Classes I, III, and IV) rely on blocking peak Na, K and L-ty...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Karagueuzian, Hrayr S., Pezhouman, Arash, Angelini, Marina, Olcese, Riccardo
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292429/
https://ncbi.nlm.nih.gov/pubmed/28220073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00036
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