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Targeting the late component of the cardiac L-type Ca(2+) current to suppress early afterdepolarizations
Early afterdepolarizations (EADs) associated with prolongation of the cardiac action potential (AP) can create heterogeneity of repolarization and premature extrasystoles, triggering focal and reentrant arrhythmias. Because the L-type Ca(2+) current (I(Ca,L)) plays a key role in both AP prolongation...
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| Publicado no: | J Gen Physiol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4411259/ https://ncbi.nlm.nih.gov/pubmed/25918358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201411288 |
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