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Early afterdepolarizations in cardiac myocytes: beyond reduced repolarization reserve

Early afterdepolarizations (EADs) are secondary voltage depolarizations during the repolarizing phase of the action potential, which can cause lethal cardiac arrhythmias. The occurrence of EADs requires a reduction in outward current and/or an increase in inward current, a condition called reduced r...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Qu, Zhilin, Xie, Lai-Hua, Olcese, Riccardo, Karagueuzian, Hrayr S., Chen, Peng-Sheng, Garfinkel, Alan, Weiss, James N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687754/
https://ncbi.nlm.nih.gov/pubmed/23619423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvt104
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