Shaping a new Ca(2+) conductance to suppress early afterdepolarizations in cardiac myocytes

NON-TECHNICAL SUMMARY: Diseases, genetic defects, or ionic imbalances can alter the normal electrical activity of cardiac myocytes causing an anomalous heart rhythm, which can degenerate to ventricular fibrillation (VF) and sudden cardiac death. Well-recognized triggers for VF are aberrations of the...

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Detalhes bibliográficos
Main Authors: Madhvani, Roshni V, Xie, Yuanfang, Pantazis, Antonios, Garfinkel, Alan, Qu, Zhilin, Weiss, James N, Olcese, Riccardo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286687/
https://ncbi.nlm.nih.gov/pubmed/22025660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.219600
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