Shaping a new Ca(2+) conductance to suppress early afterdepolarizations in cardiac myocytes

NON-TECHNICAL SUMMARY: Diseases, genetic defects, or ionic imbalances can alter the normal electrical activity of cardiac myocytes causing an anomalous heart rhythm, which can degenerate to ventricular fibrillation (VF) and sudden cardiac death. Well-recognized triggers for VF are aberrations of the...

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Main Authors: Madhvani, Roshni V, Xie, Yuanfang, Pantazis, Antonios, Garfinkel, Alan, Qu, Zhilin, Weiss, James N, Olcese, Riccardo
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2011
主題:
Cardiovascular
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286687/
https://ncbi.nlm.nih.gov/pubmed/22025660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.219600
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