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Cardiac alternans induced by fibroblast-myocyte coupling: mechanistic insights from computational models
Recent experimental studies have shown that fibroblasts can electrotonically couple to myocytes via gap junctions. In this study, we investigated how this coupling affects action potential and intracellular calcium (Ca(i)) cycling dynamics in simulated fibroblast-myocyte pairs and in two-dimensional...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Physiological Society
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2724208/ https://ncbi.nlm.nih.gov/pubmed/19482965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00341.2009 |
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