Molecular Basis of Hypokalemia-Induced Ventricular Fibrillation

BACKGROUND: Hypokalemia is known to promote ventricular arrhythmias, especially in combination with Class III antiarrhythmic drugs like dofetilide. Here we evaluated the underlying molecular mechanisms. METHODS AND RESULTS: Arrhythmias were recorded in isolated rabbit and rat hearts or patch-clamped...

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Détails bibliographiques
Publié dans:Circulation
Auteurs principaux: Pezhouman, Arash, Singh, Neha, Song, Zhen, Nivala, Michael, Eskandari, Anahita, Cao, Hong, Bapat, Aneesh, Ko, Christopher Y., Nguyen, Thao, Qu, Zhilin, Karagueuzian, Hrayr S., Weiss, James N.
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618042/
https://ncbi.nlm.nih.gov/pubmed/26269574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.115.016217
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