تحميل...
Induced overexpression of phospholemman S68E mutant improves cardiac contractility and mortality after ischemia-reperfusion
Phospholemman (PLM), when phosphorylated at Ser(68), inhibits cardiac Na(+)/Ca(2+) exchanger 1 (NCX1) and relieves its inhibition on Na(+)-K(+)-ATPase. We have engineered mice in which expression of the phosphomimetic PLM S68E mutant was induced when dietary doxycycline was removed at 5 wk. At 8–10...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Physiological Society
2014
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3962630/ https://ncbi.nlm.nih.gov/pubmed/24486513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00861.2013 |
| الوسوم: |
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