Either Non-Homologous Ends Joining or Homologous Recombination Is Required to Repair Double-Strand Breaks in the Genome of Macrophage-Internalized Mycobacterium tuberculosis

The intracellular pathogen Mycobacterium tuberculosis (Mtb) is constantly exposed to a multitude of hostile conditions and is confronted by a variety of potentially DNA-damaging assaults in vivo, primarily from host-generated antimicrobial toxic radicals. Exposure to reactive nitrogen species and/or...

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Bibliografiska uppgifter
Huvudupphovsmän: Brzostek, Anna, Szulc, Izabela, Klink, Magdalena, Brzezinska, Marta, Sulowska, Zofia, Dziadek, Jaroslaw
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962454/
https://ncbi.nlm.nih.gov/pubmed/24658131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092799
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