The role of 3-ketosteroid 1(2)-dehydrogenase in the pathogenicity of Mycobacterium tuberculosis

BACKGROUND: A growing body of evidence suggests that Mycobacterium tuberculosis (Mtb) uses the host’s cholesterol as a source of carbon and energy during infection. Strains defective in cholesterol transport or degradation exhibit attenuated growth in activated macrophages and diminished infectivity...

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Hauptverfasser: Brzezinska, Marta, Szulc, Izabela, Brzostek, Anna, Klink, Magdalena, Kielbik, Michal, Sulowska, Zofia, Pawelczyk, Jakub, Dziadek, Jaroslaw
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3599626/
https://ncbi.nlm.nih.gov/pubmed/23425360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-13-43
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